Comparative Evaluation of SMAD-2 Expression in Oral Submucous Fibrosis and Reactive Oral Lesions
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چکیده
منابع مشابه
Oral Submucous Fibrosis: A Chronic Deliberating Disease of Oral Cavity
Oral submucous fibrosis is chronic progressive condition of oral cavity. The condition is well recognized for its malignant potential. Usually the disease initiates with redness, blistering, and ulceration inside the mouth. It is characterized by progressive fibrosis of submucosal tissue. The pathogenesis of oral submucous fibrosis is not well understood. Betelquid chewing is the major etiologi...
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We describe an interesting case of oral sub mucous fibrosis accompanied by severe trismus in a 23 years old man. The patient had initially been diagnosed as having internal derangement of the temporomandibular joint and conservative treatment had failed to decrease the symptoms. Despite extremely limited temporomandibular joint movement, cone beam computed tomography revealed no important abnor...
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We aimed to assess and compare the expression of Dickkopf homolog 3 (DKK3), a possible tumor suppressor gene (TSG), in oral leukoplakia (OLK) and oral submucous fibrosis (OSF) using immunohistochemistry. Seventy-five cases of normal oral mucosa (NOM), OLK, OSF, and squamous cell carcinoma (OSCC) were studied. DKK3 was expressed in all cases of NOM, OLK and OSCC. There was steady increases in th...
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Oral submucous fibrosis (OSMF) is a potentially malignant condition that typically affects the buccal mucosa, lips, retro molar areas and the soft palate. It presents as a whitish-yellow discoloration involving the buccal mucosa, the oropharynx and rarely in the larynx. It has a chronic, insidious biological course (Chen et al., 2006). Out of all cancer i.e. oral cancer itself it is the sixth m...
متن کاملOral submucous Fibrosis: An oral physician approach
Oral submucous fibrosis is a chronic, insidious disease affecting the oral cavity and sometimes pharynx. Although occasionally preceded and/or associated with vesicle formation, is always associated with juxtaepithelial inflammatory reaction followed by fibro elastic changes in lamina propria with epithelial atrophy leading to stiffness of oral cavity leading to trismus and inability to eat. Al...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2020
ISSN: 2476-762X
DOI: 10.31557/apjcp.2020.21.2.399